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	<title>Comments on: GPs and the caveman approach to evidence</title>
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	<link>http://northerndoctor.com/2008/10/28/gps-and-the-caveman-approach-to-evidence/</link>
	<description>&#34;Science is the great antidote to the poison of enthusiasm and superstition&#34; Adam Smith.                                   A blog from a British doctor.</description>
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		<title>By: GPs and CAMapathy &#171; Northern Doctor</title>
		<link>http://northerndoctor.com/2008/10/28/gps-and-the-caveman-approach-to-evidence/#comment-469</link>
		<dc:creator>GPs and CAMapathy &#171; Northern Doctor</dc:creator>
		<pubDate>Thu, 05 Feb 2009 13:37:40 +0000</pubDate>
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		<description>[...] blogged before about some GP attitudes to evidence based medicine. Medicine is not a profession that particularly needs (or encourages) abstract concepts on a daily [...]</description>
		<content:encoded><![CDATA[<p>[...] blogged before about some GP attitudes to evidence based medicine. Medicine is not a profession that particularly needs (or encourages) abstract concepts on a daily [...]</p>
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		<title>By: northerndoctor</title>
		<link>http://northerndoctor.com/2008/10/28/gps-and-the-caveman-approach-to-evidence/#comment-313</link>
		<dc:creator>northerndoctor</dc:creator>
		<pubDate>Wed, 29 Oct 2008 13:41:23 +0000</pubDate>
		<guid isPermaLink="false">http://northerndoctor.com/?p=293#comment-313</guid>
		<description>I have to admit I was thinking more towards the woo end of the market when highlighting deficiencies GPs have when appraising evidence but it is a good point re statins. 

At the risk of sounding like I am trying to please everyone I also think Amrchair Daddy has a point. Some of these massive trials can be pretty tricksy to critique without investing a lot of time and effort (and Big Pharma can be very efficient at subtle manipulations) - I wouldn&#039;t expect GPs to get too far with this.

I also agree I would like to see much more healthy cynicism but QOF targets don&#039;t help develop that. 

Perhaps we can all agree that Big Pharma and CAM need watching very carefully.

I will put Kendrick on my reading list.</description>
		<content:encoded><![CDATA[<p>I have to admit I was thinking more towards the woo end of the market when highlighting deficiencies GPs have when appraising evidence but it is a good point re statins. </p>
<p>At the risk of sounding like I am trying to please everyone I also think Amrchair Daddy has a point. Some of these massive trials can be pretty tricksy to critique without investing a lot of time and effort (and Big Pharma can be very efficient at subtle manipulations) &#8211; I wouldn&#8217;t expect GPs to get too far with this.</p>
<p>I also agree I would like to see much more healthy cynicism but QOF targets don&#8217;t help develop that. </p>
<p>Perhaps we can all agree that Big Pharma and CAM need watching very carefully.</p>
<p>I will put Kendrick on my reading list.</p>
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		<title>By: The Armchair Daddy</title>
		<link>http://northerndoctor.com/2008/10/28/gps-and-the-caveman-approach-to-evidence/#comment-312</link>
		<dc:creator>The Armchair Daddy</dc:creator>
		<pubDate>Wed, 29 Oct 2008 10:44:16 +0000</pubDate>
		<guid isPermaLink="false">http://northerndoctor.com/?p=293#comment-312</guid>
		<description>The problem is that, having read a paper as best I can, I do not often find &#039;glaring anomolies&#039; (anomalies?). In reality it is extremely difficult to tease out problems with research papers.

I&#039;m trying to ignore the &#039;one has to wonder what else they are failing to understand&#039; bit.</description>
		<content:encoded><![CDATA[<p>The problem is that, having read a paper as best I can, I do not often find &#8216;glaring anomolies&#8217; (anomalies?). In reality it is extremely difficult to tease out problems with research papers.</p>
<p>I&#8217;m trying to ignore the &#8216;one has to wonder what else they are failing to understand&#8217; bit.</p>
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		<title>By: the A&#38;E Charge Nurse</title>
		<link>http://northerndoctor.com/2008/10/28/gps-and-the-caveman-approach-to-evidence/#comment-308</link>
		<dc:creator>the A&#38;E Charge Nurse</dc:creator>
		<pubDate>Tue, 28 Oct 2008 22:14:21 +0000</pubDate>
		<guid isPermaLink="false">http://northerndoctor.com/?p=293#comment-308</guid>
		<description>Well lets take &#039;evidence&#039; for the statins.
The NHS spends over £1 billion on them, if we add together the actual cost of the drugs, plus blood tests/manpower, etc.

Yet the cholesterol hypothesis hardly bears scrutiny - hell, there isn&#039;t even such a thing as a &quot;cholesterol level&quot; [since cholesterol is transported in lipoproteins and cannot be directly measured].

And even there was such a thing as a cholesterol level [which there isn&#039;t], then why does the so called &quot;target&quot; or threshold, presently 5 or something like that, keeps being reduced ?

Take a look at Kendricks &quot;The Cholesterol Con&quot; - if doctors can&#039;t get a handle on glaring anomolies in research evidence for statins [particularly amongst women] then one has to wonder what else they are failing to understand, or at least adopt a healthy cynicism toward [did somebody mention SSRIs] ?</description>
		<content:encoded><![CDATA[<p>Well lets take &#8216;evidence&#8217; for the statins.<br />
The NHS spends over £1 billion on them, if we add together the actual cost of the drugs, plus blood tests/manpower, etc.</p>
<p>Yet the cholesterol hypothesis hardly bears scrutiny &#8211; hell, there isn&#8217;t even such a thing as a &#8220;cholesterol level&#8221; [since cholesterol is transported in lipoproteins and cannot be directly measured].</p>
<p>And even there was such a thing as a cholesterol level [which there isn't], then why does the so called &#8220;target&#8221; or threshold, presently 5 or something like that, keeps being reduced ?</p>
<p>Take a look at Kendricks &#8220;The Cholesterol Con&#8221; &#8211; if doctors can&#8217;t get a handle on glaring anomolies in research evidence for statins [particularly amongst women] then one has to wonder what else they are failing to understand, or at least adopt a healthy cynicism toward [did somebody mention SSRIs] ?</p>
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